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Sultana Monira Hussain, M.B.B.S, M.P.H., Ph.D., from Monash University in Melbourne, Australia, and colleagues examined associations between female reproductive and hormonal factors (measured between 1990 and 1994) and incidence of total knee arthroplasty (TKA) for OA among 22,289 women participating in the Melbourne Collaborative Cohort Study. Analyses were adjusted for age, body mass index (BMI) at midlife, change in BMI from early reproductive age to midlife, country of birth, physical activity, smoking, and education level.

Source: Medical Xpress

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